23–25 Oct 2024
Milan, Italy
Europe/Rome timezone

Virtual Embryo Zoo: A Web-Based Tool for Embryogenesis Cell Tracking Visualization

24 Oct 2024, 14:00
2h 30m
Triulza Academy

Triulza Academy

Board: 44

Speaker

Teun Huijben (Chan Zuckerberg Biohub San Francisco)

Description

We present the Virtual Embryo Zoo, an innovative web app for visualizing and sharing embryo cell tracking data. This platform empowers researchers to investigate single-cell embryogenesis of six commonly studied model organisms: Drosophila, zebrafish, C. elegans, Ascidian, mouse, and Tribolium, through an intuitive and accessible web-based interface. The Virtual Embryo Zoo viewer allows users to navigate developmental stages with a time slider, select specific cells, and trace cell lineages. Lineage selections can be shared with a simple link, making it ideal for collaboration, education, and showcasing. This platform eliminates the local setup of native software, making advanced embryo lineage tracing and in silico fate mapping accessible to everyone with a browser. Developed using TypeScript, React, Vite, and three.js, our application utilizes a specialized tracking data format for asynchronous lazy data loading and on-the-fly interactivity. The online client is freely available as well as the viewer source code and data conversion scripts – so anyone can host, visualize, and interact with their own data.

Authors Teun A.P.M. Huijben*, Ashley Anderson, Andrew Sweet, Erin Hoops, Kyle Awayan, Jordão Bragantini, Loïc A. Royer
Keywords Cell tracking, 3D visualization, web-based application, embryo lineage tracing, developmental biology, open access

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